Objective: The current research is to investigate the relation between deterministic thinking and mental health among drug abusers, in which the role of  cognitive distortions is considered and clarified by focusing on deterministic thinking.

Methods: The present study is descriptive and correlative. All individuals with experience of drug abuse who had been referred to the Shafagh Rehabilitation center (Kahrizak) were considered as the statistical population. 110 individuals who were addicted to drugs (stimulants and Methamphetamine) were selected from this population by purposeful sampling to answer questionnaires about deterministic thinking and general health. For data analysis Pearson coefficient correlation and regression analysis was used.

Results: The results showed that there is a positive and significant relationship between deterministic thinking and the lack of mental health at the statistical level [r=%22, P<0.05], which had the closest relation to deterministic thinking among the factors of mental health, such as anxiety and depression. It was found that the two factors of deterministic thinking which function as the strongest variables that predict the lack of mental health are: definitiveness in predicting tragic events and future anticipation.

Discussion: It seems that drug abusers suffer from deterministic thinking when they are confronted with difficult situations, so they are more affected by depression and anxiety. This way of thinking may play a major role in impelling or restraining drug addiction.