en فیزیک درمانی Physiotherapy پژوهشي Original Research Articles <strong>Objectives</strong>: This study aims to compare, from a patient&rsquo;s perspective, the cost-effectiveness between a self-managed program and usual physiotherapy care in treating knee osteoarthritis.<br> <strong>Methods</strong>: The study participants were assigned into two groups: group I received a weekly physiotherapy treatment plus instructions on self-management skills in goal setting, pain management, exercise, healthy eating, and dealing with fatigue (self-managed group); group II had a physiotherapy session three times a week (usual care group). The osteoarthritis cost and consequence and European quality of life-5 dimension (EQ-5D) were used to generate utility scores. The health effects measure of quality-adjusted life year (QALY) was obtained, and an incremental cost-effective ratio was calculated. Cost-effectiveness was determined by plotting a cost-effectiveness plane of incremental cost against QALY obtained.<br> <strong>Results</strong>: After 8 weeks of intervention, the self-managed group recorded more significant improvements in pain level, function, and health-related quality of life than the usual care group. Clinical consultation costs (Mean&plusmn;SD NGN [Nigerian naira]=1800&plusmn;979), physiotherapy treatment costs (Mean&plusmn;SD NGN=4000&plusmn;00), and transportation costs (Mean&plusmn;SD NGN=1,940&plusmn;1,150) were less for the self-managed group than the usual care group. Imaging (x-ray) and drug costs did not differ significantly between groups. The QALYs gained over the 8-week intervention period was 0.13 for the self-management group compared to 0.11 for the usual care group.&nbsp;<br> <strong>Discussion</strong>: From the patient&rsquo;s perspective, a self-managed program was cost-effective and cheaper for healthcare resource use. Physiotherapists may adopt the program to reduce out-of-pocket expenses for patients with knee osteoarthritis. Cost-effectiveness, Self-management, Knee osteoarthritis, Physiotherapy, Nigeria 407 416 http://irj.uswr.ac.ir/browse.php?a_code=A-10-1007-1&slc_lang=en&sid=1 Wasila Habib hwasila4real@yahoo.com A-10-1007- No Department of Physiotherapy, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria. Adedapo Wasiu Awotidebe awotidebe.adedapo@gmail.com A-10-1007- 0000-0001-5666-8358 Yes Department of Physiotherapy, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria.