en کاردرمانی Occupational therapy گزارش موردي Case Reports <div style="text-align: justify;">Beaulieu-Boycott-Innes syndrome (BBIS), an autosomal recessive disorder, is characterized by dysmorphic facial features and developmental delay. In this case study, we used the age and stages questionnaire 2 (ASQ-2) to assess the developmental status of an Iranian 20-month-old girl displaying a complex BBIS phenotype. Rehabilitation interventions were designed and performed focusing on neurodevelopmental delay. Because she had a severe developmental delay and her scores in all five domains of ASQ-2 were below the cut-off points available for Iranian children, the effectiveness of rehabilitation interventions was slower than expected. It seems that early rehabilitation and close follow-up should be considered for these children. We can assume that early and properly sensory-motor and cognitive interventions in these children may lead to growth development and prevent secondary complications. &nbsp;</div> Beaulieu‐Boycott‐Innes Syndrome (BBIS), Developmental delay, Rehabilitation 503 506 http://irj.uswr.ac.ir/browse.php?a_code=A-10-100-7&slc_lang=en&sid=1 Masoud Gharib gharib_masoud@yahoo.com 0000-0002-6368-9736 Yes Orthopedic Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Roshanak Vameghi 0000-0002-7456-8008 No Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Mohsen Fallahi 0000-0002-1135-3149 No Department of Rehabilitation, Faculty of Paramedicine, Mazandaran University of Medical Sciences, Sari, Iran.