en مطالعات اپیدمیولوژیک epidemiological studies پژوهشي Original Research Articles <div style="text-align: justify;"><strong>Objectives</strong>: Since pulmonary tuberculosis (TB) treatment takes at least six months, it affects TB patients&rsquo; quality of life (QoL). This study aimed to describe the QoL of individuals affected by pulmonary TB during the initial and post-intensive treatment phases.&nbsp;<br> <strong>Methods</strong>: This cross-sectional study included 40 patients with TB in Padang City, Indonesia, for two months from February 2022. The participants were equally grouped into the intensive and post-intensive rehabilitation phases. The &ldquo;World Health Organization&rsquo;s QoL questionnaire (WHOQOL-BREF)&rdquo; measured patients&rsquo; QoL. The Mann-Whitney test pinpointed variations in patient QoL across the initial and post-intensive treatment phases.&nbsp;<br> <strong>Results</strong>: Most patients with pulmonary TB in both sets fell within the moderate QoL range. The QoL in the two-month post-intensive rehabilitation phase did not change (P>0.05). The QoL for patients with pulmonary TB showed significant variance between those in intensive and post-intensive treatment, both in physical (P<0.05) and psychological (P<0.05) domains.<br> <strong>Discussion</strong>: Patients with pulmonary TB in the intensive treatment phase experienced a diminished QoL relative to those receiving post-intensive care. Statistical analysis revealed no significant discrepancies in social relations or environmental conditions among participants in either therapy group. No discernible difference was observed in the patient&rsquo;s QoL between those receiving intensive and post-intensive pulmonary TB rehabilitation. Even if no discernible difference is observed and the patient&rsquo;s QoL somewhat declines at the start of TB treatment, it will increase with the length and effectiveness of treatment.</div> Quality of life (QoL), Pulmonary tuberculosis (TB), World Health Organization’s quality of life questionnaire (WHOQOL-BREF) 183 190 http://irj.uswr.ac.ir/browse.php?a_code=A-10-2147-1&slc_lang=en&sid=1 Najmiatul Fitria najmiatulfitria@phar.unand.ac.id 0000-0002-3255-1961 Yes Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Andalas, Padang, Indonesia. Wince Agustina winceagustina@gmail.com 0009-0004-6852-748X No Bachelor Program, Faculty of Pharmacy, Universitas Andalas, Padang, Indonesia. Yelly Oktavia Sari yellyoktavia@phar.unand.ac.id 0000-0002-8471-7054 No Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Andalas, Padang, Indonesia.