<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>Iranian Rehabilitation Journal</title>
<title_fa>مجله انگلیسی زبان توانبخشی</title_fa>
<short_title>Iranian Rehabilitation Journal</short_title>
<subject>Medical Sciences</subject>
<web_url>http://irj.uswr.ac.ir</web_url>
<journal_hbi_system_id>18</journal_hbi_system_id>
<journal_hbi_system_user>agent2</journal_hbi_system_user>
<journal_id_issn>17353602</journal_id_issn>
<journal_id_issn_online>17353610</journal_id_issn_online>
<journal_id_pii></journal_id_pii>
<journal_id_doi>10.29252/nrip.irj</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid></journal_id_sid>
<journal_id_nlai></journal_id_nlai>
<journal_id_science></journal_id_science>
<language>en</language>
<pubdate>
	<type>jalali</type>
	<year>1403</year>
	<month>1</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2024</year>
	<month>4</month>
	<day>1</day>
</pubdate>
<volume>0</volume>
<number>Accepted article</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>en</language>
	<article_id_doi></article_id_doi>
	<title_fa></title_fa>
	<title>Perceptual Speech Outcomes and Single-View Videofluoroscopic Findings After Radical Intravelar Veloplasty: A Retrospective Audit</title>
	<subject_fa>گفتار درمانی</subject_fa>
	<subject>Speech therapy</subject>
	<content_type_fa>پژوهشي</content_type_fa>
	<content_type>Original Research Articles</content_type>
	<abstract_fa></abstract_fa>
	<abstract>&lt;span style=&quot;line-height:normal&quot;&gt;&lt;b&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;Objectives:&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;Velopharyngeal insufficiency (VPI) is a persistent complication after primary palatoplasty that adversely affects speech. Radical intravelar veloplasty (IVVP) has been proposed as a secondary reconstructive technique aimed at restoring velopharyngeal function. This study aimed to evaluate speech outcomes and velopharyngeal closure following radical IVVP in non-syndromic cleft palate patients.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;b&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;Methods&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;This retrospective audit comprised 94 patients who underwent perceptual speech evaluations pre- and postoperatively. Parameters assessed included hypernasality (HN), audible nasal emission (ANE), and non-oral errors (NOEs). In a subgroup of 53 patients, single-view lateral videofluoroscopy was used to measure the velopharyngeal closure ratio (VPCR). Statistical analyses were performed using Wilcoxon and paired t-tests, and ordinal logistic regression (p &lt; 0.05).&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;b&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;Results&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;Postoperative assessments at a minimum of 6 months (median follow-up: 15 months) demonstrated significant reductions in HN (p &lt; 0.001&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;, r = 0.65), ANEs (p = 0.001, r = 0.33), and NOE (p&lt;0.001, r=0.43)&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;. VPCR improved significantly (from 0.48 to 0.70, p &lt; 0.001, r = 0.07), and complete closure was achieved in 13 patients. The fistula rate decreased significantly from 21.2% to 7.4% (p = 0.002). The ordinal logistic regression model indicated that Preoperative NOEs (&amp;beta; = &amp;minus;1.59, OR = 0.20, p = 0.02), age at surgery (&amp;beta; = 0.08, OR =1.08, p=0.04), and postoperative VPCR (&amp;beta;=&amp;minus;0.29, OR=0.75, p=0.05) were statistically significant predictors of the outcome (All p&amp;le;0.05).&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;b&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;Discussion&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;This study evaluated the outcomes of IVVP in non-syndromic cleft palate patients. &amp;nbsp;It demonstrated significant improvements in speech characteristics, a reduction in fistula rate, and an increase in VPCR. Nevertheless, many patients retained residual HN or required subsequent surgical intervention, underscoring the complexity of speech management. Younger age at surgery and fewer preoperative non&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span cambria=&quot;&quot; math=&quot;&quot; style=&quot;font-family:&quot;&gt;‑&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;oral errors were associated with better outcomes, while VPCR improvement was associated with reduced HN severity, it did not consistently predict complete perceptual normalization. These findings emphasize the importance of early intervention and combined perceptual and instrumental assessment in postoperative management.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;b&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;Conclusion&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;Radical IVVP achieves significant functional improvement across key speech parameters and velopharyngeal (VP) function&lt;/span&gt;&lt;/span&gt; &lt;span lang=&quot;EN-US&quot; style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;in appropriately selected cleft palate patients. However, VPCR alone is insufficient to fully predict resonance outcomes.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&amp;nbsp;</abstract>
	<keyword_fa></keyword_fa>
	<keyword>Radical Intravelar Veloplasty, Velopharyngeal insufficiency, Speech outcomes, Secondary palatoplasty, Hypernasality</keyword>
	<start_page>0</start_page>
	<end_page>0</end_page>
	<web_url>http://irj.uswr.ac.ir/browse.php?a_code=A-10-2614-2&amp;slc_lang=en&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Fatemeh</first_name>
	<middle_name></middle_name>
	<last_name>Derakhshandeh</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>derakhshandeh@rehab.mui.ac.ir</email>
	<code>0000-0003-0261-050X</code>
	<orcid></orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation>Ph.D. Assistant Professor in Speech Therapy, Craniofacial and Cleft Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>mehri</first_name>
	<middle_name></middle_name>
	<last_name>tavakoli</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>tavakkoli.mehri@ymail.com</email>
	<code>0009-0009-8648-1637</code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>MSc in Speech Therapy, Craniofacial and Cleft Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Parisa</first_name>
	<middle_name></middle_name>
	<last_name>Rezaei</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>parisa.re.8946@gmail.com</email>
	<code>0000-0002-2430-8822</code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Ph.D. Student in Speech Therapy, Rehabilitation Research Center, Department of Speech and Language Pathology, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Neda</first_name>
	<middle_name></middle_name>
	<last_name>Tahmasebifaed</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>ntahmasebifard@saintmarys.edu</email>
	<code>0009-0003-6109-2009</code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>PhD, Department of Speech and Language Pathology, Saint Mary’s College, Notre Dame, Indiana, USA</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Hossein</first_name>
	<middle_name></middle_name>
	<last_name>Abdali</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>abdali@med.mui.ac.ir</email>
	<code>0000-0003-1421-4504</code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>MD. Ph.D. Plastic Surgeon, Craniofacial and Cleft Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
