en روانشناسی Psychology پژوهشي Original Research Articles <div style="text-align: justify;"><strong>Objectives</strong>: Deaf and hard-of-hearing (DHH) people experience a variety of psychological distress. The quality of life (QoL), health, stress, anxiety, and depression in DHH adolescents can affect their psychological well-being. This study aimed to predict psychological well-being based on psychosocial factors in DHH adolescents.&nbsp;<br> <strong>Methods</strong>: A total of 120 DHH adolescents participated in the current cross-sectional study. Adolescents were chosen through a convenient sampling method from secondary deaf schools in Isfahan, Iran in 2020. These adolescents were assessed with the KIDSCREEN-27 health-related QoL questionnaire, youth QoL instrument-deaf and hard of hearing (YQOL-DHH), and depression, anxiety, stress scales (DASS-21).&nbsp;<br> <strong>Results</strong>: Perceived stigma, stress, anxiety, and depression had a significant and negative relationship with psychological well-being, while self-advocacy/acceptance, participation, physical well-being, social support, school environment, and parent relations had a significant and positive relationship with the psychological well-being of DHH adolescents. These variables predicted 89% of the psychological well-being of these adolescents.&nbsp;<br> <strong>Discussion</strong>: Findings suggest that the QoL, health, stress, anxiety, and depression were significant predictors of the well-being of DHH adolescents.&nbsp;</div> Anxiety, Depression, Health, Quality of life, Stress, Well-being 25 34 http://irj.uswr.ac.ir/browse.php?a_code=A-10-188-9&slc_lang=en&sid=1 Mohammad Ashori m.ashori@edu.ui.ac.ir 0000-0002-1685-2932 Yes Department of Psychology and Education of People with Special Needs, Faculty of Education and Psychology, University of Isfahan, Isfahan, Iran. Bahar Rashidi aa.rashidi391@yahoo.com 0000-0003-2919-2045 No Department of Psychology and Education of People with Special Needs, Faculty of Education and Psychology, University of Isfahan, Isfahan, Iran.