en کاردرمانی Occupational therapy پژوهشي Original Research Articles <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Tahoma;"><span style="line-height:2;"><strong>Objectives</strong>: Limitations in the ability to perform manual functions decrease the individual&rsquo;s participation in activities of daily living (ADLs). Thus, it is required to study the relationship between manual skills and self-care activities in children. This study aims to investigate the relationship between manual ability and self-care in children with spastic cerebral palsy at the ages of 1 to 8 years.<br> <strong>Methods</strong>: In this cross-sectional study, 125 children aged 1-8 years with spastic cerebral palsy who were chosen by the convenience sampling method from 8 occupational therapy clinics in Tehran City, Iran, in 2022 were studied. The evaluation tools were manual ability classification system (MACS), mini-manual ability classification system (Mini-MACS), pediatric evaluation of disability inventory (PEDI), and cognitive level form designed in the SPARCLE project. After collecting the data, Stata software, version 14 was used to analyze data using chi-square, Spearman correlation coefficient, Mann-Whitney, Kruskal-Wallis, and regression.<br> <strong>Results</strong>: In this research, the mean age of the children was 54.2&plusmn;15 months and 43.2% had a cognitive level >70. The mean self-care and mobility in children were 49.65&plusmn;30.60 and 40.78&plusmn;26.97, respectively. With increasing age, self-care and mobility of children showed a significant increase (P<0.001). No significant difference was observed between boys and girls in self-care and mobility (P<0.05). By changing the education level of the main caregiver, no significant difference was found in self-care and mobility (P<0.05). With the increase in children&rsquo;s cognitive ability level and MACS level, self-care and mobility improved significantly (P<0.001). Moreover, the level of MACS and mobility with the highest beta values (-0.530 and 0.512, respectively) showed a greater contribution to the prediction of self-care.<br> <strong>Discussion</strong>: The results showed that with increasing age, cognitive ability level, and MACS level, self-care and mobility improve significantly in children with spastic cerebral palsy. Therefore, it is suggested to pay more attention to manual ability to improve self-care and mobility in these children.</span></span></span></div> Manual ability classification system (MACS), Mobility, Self-care, Spastic cerebral palsy 601 610 http://irj.uswr.ac.ir/browse.php?a_code=A-10-160-4&slc_lang=en&sid=1 Mohammad Amiri amiri.otm@gmail.com 0009-0006-7743-0174 No Department of Occupational Therapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran. Hamid Dalvand hamiddalvand@gmail.com 0000-0003-2725-5081 Yes Department of Occupational Therapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran. Mehdi Rassafiani mrassafiani@yahoo.com 0000-0003-4093-6113 No School of Allied Health, Exercise and Sports Sciences, Charles Sturt University, Bathurst, Australia. Amir Almasi amiralmasi2007@gmail.com 0000-0003-4434-561x No Department of Epidemiology, School of Health, Arak University of Medical Sciences, Arak, Iran.