Volume 17, Issue 4 (December 2019)                   Iranian Rehabilitation Journal 2019, 17(4): 385-394 | Back to browse issues page

DOI: 10.32598/irj.17.4.385

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1- Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Abstract:   (971 Views)
Objectives: The modulation of the dorsolateral prefrontal cortex (DLPFC) activity enhanced the prospects of substance use disorders rehabilitation, using non-invasive brain stimulation, such as transcranial Direct Current Stimulation (tDCS).
Methods: We carried out a randomized sham-controlled clinical trial to assess the effect of repeated tDCS at DLPFC on drug craving in 30 abstinent male methamphetamine users. The participants underwent 5 sessions of 20 minutes bilateral real or sham 2 mA tDCS (anode right/ cathode left) of DLPFC. The Desire for Drug Questionnaire (DDQ) was used for assessing instant craving. The cue-induced craving was rated on a Visual Analog Scale (VAS) after the verbal induction of craving.
Results: The findings of this study indicated that cue-induced craving reduced significantly in tDCS related to sham (P<0.05), but tDCS did not significantly alter instant craving.
Discussion: The results indicated that repeated bilateral tDCS over DLPFC was not effective in reducing self-report instant craving, but reduced self-reported craving in the craving induction condition.
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Type of Study: Original Research Articles | Subject: Psychology
Received: 2018/01/8 | Accepted: 2018/04/5 | Published: 2019/12/29