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Volume 18, Issue 2 (June 2020)
Iranian Rehabilitation Journal 2020, 18(2): 137-144 |
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Mousavi E, Hosseini S, Bakhtiyari M, Abasi I, Mohammadi A, Masjedi Arani A. The Effects of Mindfulness-based Stress Reduction Group Therapy on Anxiety, Depression, Stress, and the Intolerance of Uncertainty in Infertile Women. Iranian Rehabilitation Journal 2020; 18 (2) :137-144
URL: http://irj.uswr.ac.ir/article-1-988-en.html
URL: http://irj.uswr.ac.ir/article-1-988-en.html
Elnaz Mousavi * 
1, Sedighe Hosseini2 , Maryam Bakhtiyari3 , Imaneh Abasi3 , Abolfazl Mohammadi4 , Abbas Masjedi Arani5
1, Sedighe Hosseini2 , Maryam Bakhtiyari3 , Imaneh Abasi3 , Abolfazl Mohammadi4 , Abbas Masjedi Arani5
1- Department of Clinical Psychology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
2- In Vitro Fertilization (IVF Center), Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3- Depatment of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4- Department of Psychiatry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
5- Department of Community Medicine, Quran and Hadith Reasearch Center, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
2- In Vitro Fertilization (IVF Center), Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3- Depatment of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4- Department of Psychiatry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
5- Department of Community Medicine, Quran and Hadith Reasearch Center, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Keywords: Mindfulness-based stress reduction, Anxiety, Depression, Stress, Intolerance of uncertainty, In vitro Fertilization (IVF)
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The Depression Anxiety Stress Scale (DASS), and the Intolerance of Uncertainty Scale (IUS) were administered for data collection. The research participants in the MBSR group (n=15) received therapy for 8 weekly sessions (2 hours); however, the control group (n=15) received no treatment. The diagnostic evaluation tools were administered at pre-test, post-test, and the 3-month follow-up stages. A summary of functional instruction sessions of MBSR is illustrated in Table 1. The therapist of the present study was a PhD. student of Clinical Psychology and had already received the training and courses for MBSR. Moreover, the evaluator of this study held a master’s degree in Clinical Psychology to avoid bias concerning the study findings. The obtained data were analyzed using SPSS.
The below instruments were used in the present research.
Structured Clinical Interview (SCID-I/SCID-II)
This tool was developed by Frist et al. in 1997. It is used for diagnosis based on 4 criteria of the Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition (DSM-IV). SCID has two versions; 1- SCID-I for assessing axis I. This tool has excellent validity and reliability. For instance, Bakhtiari’s study (2000) has supported the validity of this tool. 2- SCID-II is employed for assessing axis II. It measures 10 personality disorders, based on DSM-IV criteria, as well as a passive personality disorder. In Bakhtiari’s study, the content validity of the translated version of the tool was established by three professors of Psychology. Additionally, the test-retest reliability coefficient of this tool with an interval of one week was calculated as 87% [13].
The 21-item Anxiety, Depression, and Stress Scale (DASS-21)
The short form of this scale with 42 questions has been generated by Leviband in 1995. Its test-retest reliability for depression, anxiety, and stress is reported to be 80%, 76%, and 77%. Moreover, these aspects’ Chronbach’s alpha coefficient was measured as 81%, 79%, and 78%, respectively. The validity of this tool was examined by confirmatory factor analysis and components method. The cut-off points of anxiety, depression, and stress were reported as 7, 9, and 14, respectively [14]. In Sahebi’s study, the reliability of this tool for depression, anxiety, and stress were reported 0.77, 0.79, and 0.78, respectively [13].
The Intolerance of Uncertainty Scale (IUS)
This scale was designed by Freestone. The test has 27 questions, i.e. related to unacceptability and ambiguity. This test is answered on a five-point Likert-type scale (never, rarely, sometimes, often, & always). Besides, each option is scored with 1, 2, 3, 4, and 5, respectively. The cut-off point of the questionnaire was measured as 54 [15]. In the French version, the internal consistency (0.91) and a relatively good retest reliability coefficient were obtained with a 4-week interval (0.78). The coefficient of the validity of this test was reported to be significant and satisfactory [16]. In the research of Alizadeh, Hasanzadeh, Aliloo, and Poursharifi, the Cronbach’s alpha coefficient of the total uncertainty imbalance was computed as 0.69 [17].
3. Results
Adherence was measured by the percentage of completed prescribed homework. About 90% of homework was completed by the study participants. There was no drop out in the treatment group during the intervention and at the follow-up stage. Before analyzing the differences between MBSR and control groups in study variables, the differences in demographic variables were examined. The results of the Independent Samples t-test and Chi-squared test demonstrated no significant differences in age (t28=-1.07, P<0.29) and educational level (χ(3)2=1.36, P=0.73) between the MBSR and control groups.
At baseline assessment, there were no significant differences between the study groups in stress (t28=-1.28, P=0.21) and IU (t28=0.29, P=0.76); however, there were significant differences between the research groups in depression (t28=2.74, P=0.01) and anxiety (t28=2.06, P=0.04) symptoms.
The Mean±SD age of the control and MBSR groups was 36.20±5.11 and 34.27±4.75 years, respectively. The Mean±SD scores of the explored dependent variables are presented in Table 2.
The Independent Samples t-test and Analysis of Covariance (ANCOVA) (after assessing the homogeneity of variances, i.e. not significant) were implemented to examine the differences between groups in terms of the dependent variables. The relevant results indicated a significant difference between the MBSR and control groups in IU (t28=-2.56, P<0.01), stress (t28=-4.34, P<0.001), depression (F1,28=122.33, P<0.001, η2=0.81), and anxiety (F1,28=105.22, P<0.001, η2=0.79). Furthermore, to examine the effects of MBSR on the dependent variables and whether treatment efficacy was maintained at the 3-months follow-up, a Paired Samples t-test was conducted (Table 3). The obtained data suggested significant differences in all explored dependent variables between pre-test and post-test phases scores, except for IU.
To assess clinical significance, the total mean value of the experimental group concerning stress, depression, anxiety, and IU was assessed after conducting the intervention. All mean scores were below the mentioned cut-off point (stress: 5, depression: 10.40, & anxiety: 10), except for IU (57.26).
4. Discussion
The current study examined the effectiveness of MBSR group therapy on anxiety, depression, stress, and IU in infertile women receiving IVF. The collected results suggested that MBSR is effective on anxiety, depression, the stress in infertile women receiving IVF; however, it had no significant effect on IU in the studied females. The obtained data concerning the effectiveness of this treatment on anxiety, depression, and stress were consistent with the study of Li [4], Baer [18], Dembinska [19], Aslzaker [11], and Nery [13]. Theorists have suggested that MBSR may decrease the symptoms of stress, anxiety, and depression by adjusting emotion regulation skills [20].
Furthermore, clinical observations highlighted that IU plays an essential role in increasing worry and rumination [21]. Concerning the effectiveness of MBSR on IU in this group, the current research results suggested no effects of the provided treatment on IU in the investigated participants. This finding was consistent with those of previous research [22]. However, they were inconsistent with the results of Vered Miriam [23] and Lee [24]. In explaining our results, research reflects a correlation between IU and metacognition, i.e. anticipated that both factors play critical roles in maintaining worry. It could be hypothesized that having certain thoughts about cognitions could affect how one processes the content of thoughts, especially those about uncertainty [25]. Thus, IU is a potential characteristic in infertile women receiving IVF and psychopathology at the “macro” cognitive level; that is why MBSR was ineffective on it.
MBSR techniques are more effective in changing emotions [20]. Furthermore, IU is more of a cognitive component rather than an emotional one; thus, probably because of this, the treatment failed to affect it. Another explanation is that clients with high IU experience substantial discomfort when confronting uncertainty. Such a condition causes them to be highly motivated to avoid or minimize any aspects of psychotherapy that focus on change. This may cause them to avoid confronting their problems during the action stage of therapy [26]. Moreover, another reason for gaining this result might be the applied questionnaire that fails to match our culture [15].
Limiting the study sample to Tehran restricts the generalizability of the obtained results to other regions. Another limitation of the study was the lack of involvement of men in the program, which also reduces the generalizability of the results. The lack of specific objective assessments could be considered as a factor limiting the research. Researchers suggest that the MBSR be implemented on infertile couples and to use large sample sizes. Additionally, it is recommended that further studies consider the effectiveness of other therapeutic protocols as well as the impact of IU among infertile women receiving IVF.
5. Conclusion
MBSR could decrease anxiety, stress, and depression in infertile women receiving IVF; these therapeutic outcomes remained at a 3-month follow-up, especially for depression, anxiety, and stress symptoms. However in terms of the IU, due to the nature of this variable, the treatment type and the impact of the questionnaire were not effective and significant.
Ethical Considerations
Compliance with ethical guidelines
The study was approved by the Ethics Committee of Shahid Behesht University of Medical Sciences (Code: IR.SBMU.MSP.REC.96233). Also all study participants were informed about the study objectives and those agreeing to participate signed the informed consent forms.
Funding
This research was financially supported by Shahid Beheshti University of Medical Sciences.
Authors' contributions
Conceptualization, supervision: Abbas Masjedi Arani; Methodology: Maryam Bakhtiyari; Investigation: Sedighe Hosseini; Writing – original draft, resources: Elnaz Mousavi; Formal analysis: Imaneh Abasi; Review & editing: Abolfazl Mohammadi.
Conflict of interest
The authors declared no conflicts of interest.
References
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Full-Text: (1210 Views)
1. Introduction
nfertility is a complex problem that affects the life of approximately 80 million individuals in the world. Furthermore, it is estimated that mental problems in infertile people range from 60%-25%, and in particular, anxiety and depression in infertile groups [1]. Stress, depression, anger, and anxiety are associated with infertility in women [2]. Numerous studies demonstrated that mental health factors, e.g. depression or anxiety could threaten infertility treatment outcomes [3]. In addition to anxiety and depression, many psychological variables affect the treatment outcomes in infertile individuals [4]. For example, the Intolerance of Uncertainty (IU) affects the rate of depression, anxiety, and stress in this population. The IU could be defined as a cognitive bias on how individuals perceive, interpret, and respond to uncertain situations, which affects their cognitive, emotional, and behavioral aspects [5].
Some early psychological theories have suggested that the tendency to avoid uncertainties significantly impact the severity and continuation of depression and anxiety [6]. The initiation of infertility interventions is regularly a difficult decision for the couples. This is because it is connected with the stress associated with the inability to naturally become pregnant and losing control over their bodies. There are some approaches for fertility that intrauterine insemination; In Vitro Fertilization (IVF) is one of these methods [7]. Many of the infertile couples end up using IVF as a procedure of fertility. A consequence of such interventions is the increased stress level and the outcome of the IVF process [8]. Therefore, researchers suggested that an infertility treatment program must be accompanied by psychological treatment [9].
The Mindfulness-based Stress Reduction (MBSR) program is a third-generation of cognitive-behavioral therapies. MBSR includes education about stress as well as training in coping strategies. MBSR involves the development of some attitudes, including becoming an unbiased witness to one’s own experience; the acceptance of matters as they are in the present moment; and not censoring thoughts and allowing them to come and go [10]. Li et al [4] argued that mindfulness helped infertile women to cope with IVF in adaptive manners. Additionally, Aslzaker [11] suggested that MBSR is effective in the success of IVF and psychological symptoms in women receiving IVF.
Infertility may not be regarded as a medical problem; however, because each couple suffering from this issue spends a lot of time and money to solve this matter. They also have many relatives might pressurize them; thus, studying infertility is necessary [12]. Investigating the most effective psychological interventions to reduce anxiety, depression, stress, and IU in infertile women could be sensitive and constructive in improving the effects of moderen infertility treatments and reduce the failure of IVF therapy in this group. Exploring IU has been neglected in previous studies. Therefore, this study aimed to investigate the effects of MBSR group therapy on anxiety, depression, stress, and IU in infertile women receiving IVF.
2. Methods
This was a clinical trial with a pre-test/post-test and a control group design. The statistical population of this study was infertile women aged 20-45 years presenting the symptoms of anxiety and depression in Tehran Province, Iran, in 2017-2018. The study participants consisted of 30 infertile women with their age ranging from 26 to 43 years (Mean±SD: 35.23±4.95) referring to Taleghani Hospital in Tehran City, Iran in 2017-2018. The required sample size was calculated based on G* Power software with an alpha error of 0.05 and a beta error of 0.2. Besides, the effect size equaled 0.25, and the number of repetitions was equal to 3. The study participants were randomly assigned to the study groups. In terms of educational level, 3.3%, 43.3%, 36.7%, and 16.7% were identified as under diploma, diploma, bachelor’s degree, and master’s degree, respectively.
After referral by infertility specialist, the study subjects were selected using The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) and The Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II). We employed a purposive sampling method for selecting the study samples. The study inclusion criteria were as follows: at least one year past marriage, receiving a definite diagnosis of infertility, having elementary education and higher, women aged 20-45 years, the lack of receiving prior IVF/ICSI treatment, agreeing to participate in the treatment, the lack of hormonal and genital diseases, no history of separation and remarriage, not having a child, no history of acute psychiatric disorders, and not consuming psychiatric medications. Additionally, the study exclusion criteria were as follows: absence from more than two sessions of MBSR treatment, ant no willingness to continue the treatment. The flowchart of study participants is listed in Figure 1.
nfertility is a complex problem that affects the life of approximately 80 million individuals in the world. Furthermore, it is estimated that mental problems in infertile people range from 60%-25%, and in particular, anxiety and depression in infertile groups [1]. Stress, depression, anger, and anxiety are associated with infertility in women [2]. Numerous studies demonstrated that mental health factors, e.g. depression or anxiety could threaten infertility treatment outcomes [3]. In addition to anxiety and depression, many psychological variables affect the treatment outcomes in infertile individuals [4]. For example, the Intolerance of Uncertainty (IU) affects the rate of depression, anxiety, and stress in this population. The IU could be defined as a cognitive bias on how individuals perceive, interpret, and respond to uncertain situations, which affects their cognitive, emotional, and behavioral aspects [5].
Some early psychological theories have suggested that the tendency to avoid uncertainties significantly impact the severity and continuation of depression and anxiety [6]. The initiation of infertility interventions is regularly a difficult decision for the couples. This is because it is connected with the stress associated with the inability to naturally become pregnant and losing control over their bodies. There are some approaches for fertility that intrauterine insemination; In Vitro Fertilization (IVF) is one of these methods [7]. Many of the infertile couples end up using IVF as a procedure of fertility. A consequence of such interventions is the increased stress level and the outcome of the IVF process [8]. Therefore, researchers suggested that an infertility treatment program must be accompanied by psychological treatment [9].
The Mindfulness-based Stress Reduction (MBSR) program is a third-generation of cognitive-behavioral therapies. MBSR includes education about stress as well as training in coping strategies. MBSR involves the development of some attitudes, including becoming an unbiased witness to one’s own experience; the acceptance of matters as they are in the present moment; and not censoring thoughts and allowing them to come and go [10]. Li et al [4] argued that mindfulness helped infertile women to cope with IVF in adaptive manners. Additionally, Aslzaker [11] suggested that MBSR is effective in the success of IVF and psychological symptoms in women receiving IVF.
Infertility may not be regarded as a medical problem; however, because each couple suffering from this issue spends a lot of time and money to solve this matter. They also have many relatives might pressurize them; thus, studying infertility is necessary [12]. Investigating the most effective psychological interventions to reduce anxiety, depression, stress, and IU in infertile women could be sensitive and constructive in improving the effects of moderen infertility treatments and reduce the failure of IVF therapy in this group. Exploring IU has been neglected in previous studies. Therefore, this study aimed to investigate the effects of MBSR group therapy on anxiety, depression, stress, and IU in infertile women receiving IVF.
2. Methods
This was a clinical trial with a pre-test/post-test and a control group design. The statistical population of this study was infertile women aged 20-45 years presenting the symptoms of anxiety and depression in Tehran Province, Iran, in 2017-2018. The study participants consisted of 30 infertile women with their age ranging from 26 to 43 years (Mean±SD: 35.23±4.95) referring to Taleghani Hospital in Tehran City, Iran in 2017-2018. The required sample size was calculated based on G* Power software with an alpha error of 0.05 and a beta error of 0.2. Besides, the effect size equaled 0.25, and the number of repetitions was equal to 3. The study participants were randomly assigned to the study groups. In terms of educational level, 3.3%, 43.3%, 36.7%, and 16.7% were identified as under diploma, diploma, bachelor’s degree, and master’s degree, respectively.
After referral by infertility specialist, the study subjects were selected using The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) and The Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II). We employed a purposive sampling method for selecting the study samples. The study inclusion criteria were as follows: at least one year past marriage, receiving a definite diagnosis of infertility, having elementary education and higher, women aged 20-45 years, the lack of receiving prior IVF/ICSI treatment, agreeing to participate in the treatment, the lack of hormonal and genital diseases, no history of separation and remarriage, not having a child, no history of acute psychiatric disorders, and not consuming psychiatric medications. Additionally, the study exclusion criteria were as follows: absence from more than two sessions of MBSR treatment, ant no willingness to continue the treatment. The flowchart of study participants is listed in Figure 1.
The Depression Anxiety Stress Scale (DASS), and the Intolerance of Uncertainty Scale (IUS) were administered for data collection. The research participants in the MBSR group (n=15) received therapy for 8 weekly sessions (2 hours); however, the control group (n=15) received no treatment. The diagnostic evaluation tools were administered at pre-test, post-test, and the 3-month follow-up stages. A summary of functional instruction sessions of MBSR is illustrated in Table 1. The therapist of the present study was a PhD. student of Clinical Psychology and had already received the training and courses for MBSR. Moreover, the evaluator of this study held a master’s degree in Clinical Psychology to avoid bias concerning the study findings. The obtained data were analyzed using SPSS.
The below instruments were used in the present research.
Structured Clinical Interview (SCID-I/SCID-II)
This tool was developed by Frist et al. in 1997. It is used for diagnosis based on 4 criteria of the Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition (DSM-IV). SCID has two versions; 1- SCID-I for assessing axis I. This tool has excellent validity and reliability. For instance, Bakhtiari’s study (2000) has supported the validity of this tool. 2- SCID-II is employed for assessing axis II. It measures 10 personality disorders, based on DSM-IV criteria, as well as a passive personality disorder. In Bakhtiari’s study, the content validity of the translated version of the tool was established by three professors of Psychology. Additionally, the test-retest reliability coefficient of this tool with an interval of one week was calculated as 87% [13].
The 21-item Anxiety, Depression, and Stress Scale (DASS-21)
The short form of this scale with 42 questions has been generated by Leviband in 1995. Its test-retest reliability for depression, anxiety, and stress is reported to be 80%, 76%, and 77%. Moreover, these aspects’ Chronbach’s alpha coefficient was measured as 81%, 79%, and 78%, respectively. The validity of this tool was examined by confirmatory factor analysis and components method. The cut-off points of anxiety, depression, and stress were reported as 7, 9, and 14, respectively [14]. In Sahebi’s study, the reliability of this tool for depression, anxiety, and stress were reported 0.77, 0.79, and 0.78, respectively [13].
The Intolerance of Uncertainty Scale (IUS)
This scale was designed by Freestone. The test has 27 questions, i.e. related to unacceptability and ambiguity. This test is answered on a five-point Likert-type scale (never, rarely, sometimes, often, & always). Besides, each option is scored with 1, 2, 3, 4, and 5, respectively. The cut-off point of the questionnaire was measured as 54 [15]. In the French version, the internal consistency (0.91) and a relatively good retest reliability coefficient were obtained with a 4-week interval (0.78). The coefficient of the validity of this test was reported to be significant and satisfactory [16]. In the research of Alizadeh, Hasanzadeh, Aliloo, and Poursharifi, the Cronbach’s alpha coefficient of the total uncertainty imbalance was computed as 0.69 [17].
3. Results
Adherence was measured by the percentage of completed prescribed homework. About 90% of homework was completed by the study participants. There was no drop out in the treatment group during the intervention and at the follow-up stage. Before analyzing the differences between MBSR and control groups in study variables, the differences in demographic variables were examined. The results of the Independent Samples t-test and Chi-squared test demonstrated no significant differences in age (t28=-1.07, P<0.29) and educational level (χ(3)2=1.36, P=0.73) between the MBSR and control groups.
At baseline assessment, there were no significant differences between the study groups in stress (t28=-1.28, P=0.21) and IU (t28=0.29, P=0.76); however, there were significant differences between the research groups in depression (t28=2.74, P=0.01) and anxiety (t28=2.06, P=0.04) symptoms.
The Mean±SD age of the control and MBSR groups was 36.20±5.11 and 34.27±4.75 years, respectively. The Mean±SD scores of the explored dependent variables are presented in Table 2.
The Independent Samples t-test and Analysis of Covariance (ANCOVA) (after assessing the homogeneity of variances, i.e. not significant) were implemented to examine the differences between groups in terms of the dependent variables. The relevant results indicated a significant difference between the MBSR and control groups in IU (t28=-2.56, P<0.01), stress (t28=-4.34, P<0.001), depression (F1,28=122.33, P<0.001, η2=0.81), and anxiety (F1,28=105.22, P<0.001, η2=0.79). Furthermore, to examine the effects of MBSR on the dependent variables and whether treatment efficacy was maintained at the 3-months follow-up, a Paired Samples t-test was conducted (Table 3). The obtained data suggested significant differences in all explored dependent variables between pre-test and post-test phases scores, except for IU.
To assess clinical significance, the total mean value of the experimental group concerning stress, depression, anxiety, and IU was assessed after conducting the intervention. All mean scores were below the mentioned cut-off point (stress: 5, depression: 10.40, & anxiety: 10), except for IU (57.26).
4. Discussion
The current study examined the effectiveness of MBSR group therapy on anxiety, depression, stress, and IU in infertile women receiving IVF. The collected results suggested that MBSR is effective on anxiety, depression, the stress in infertile women receiving IVF; however, it had no significant effect on IU in the studied females. The obtained data concerning the effectiveness of this treatment on anxiety, depression, and stress were consistent with the study of Li [4], Baer [18], Dembinska [19], Aslzaker [11], and Nery [13]. Theorists have suggested that MBSR may decrease the symptoms of stress, anxiety, and depression by adjusting emotion regulation skills [20].
Furthermore, clinical observations highlighted that IU plays an essential role in increasing worry and rumination [21]. Concerning the effectiveness of MBSR on IU in this group, the current research results suggested no effects of the provided treatment on IU in the investigated participants. This finding was consistent with those of previous research [22]. However, they were inconsistent with the results of Vered Miriam [23] and Lee [24]. In explaining our results, research reflects a correlation between IU and metacognition, i.e. anticipated that both factors play critical roles in maintaining worry. It could be hypothesized that having certain thoughts about cognitions could affect how one processes the content of thoughts, especially those about uncertainty [25]. Thus, IU is a potential characteristic in infertile women receiving IVF and psychopathology at the “macro” cognitive level; that is why MBSR was ineffective on it.
MBSR techniques are more effective in changing emotions [20]. Furthermore, IU is more of a cognitive component rather than an emotional one; thus, probably because of this, the treatment failed to affect it. Another explanation is that clients with high IU experience substantial discomfort when confronting uncertainty. Such a condition causes them to be highly motivated to avoid or minimize any aspects of psychotherapy that focus on change. This may cause them to avoid confronting their problems during the action stage of therapy [26]. Moreover, another reason for gaining this result might be the applied questionnaire that fails to match our culture [15].
Limiting the study sample to Tehran restricts the generalizability of the obtained results to other regions. Another limitation of the study was the lack of involvement of men in the program, which also reduces the generalizability of the results. The lack of specific objective assessments could be considered as a factor limiting the research. Researchers suggest that the MBSR be implemented on infertile couples and to use large sample sizes. Additionally, it is recommended that further studies consider the effectiveness of other therapeutic protocols as well as the impact of IU among infertile women receiving IVF.
5. Conclusion
MBSR could decrease anxiety, stress, and depression in infertile women receiving IVF; these therapeutic outcomes remained at a 3-month follow-up, especially for depression, anxiety, and stress symptoms. However in terms of the IU, due to the nature of this variable, the treatment type and the impact of the questionnaire were not effective and significant.
Ethical Considerations
Compliance with ethical guidelines
The study was approved by the Ethics Committee of Shahid Behesht University of Medical Sciences (Code: IR.SBMU.MSP.REC.96233). Also all study participants were informed about the study objectives and those agreeing to participate signed the informed consent forms.
Funding
This research was financially supported by Shahid Beheshti University of Medical Sciences.
Authors' contributions
Conceptualization, supervision: Abbas Masjedi Arani; Methodology: Maryam Bakhtiyari; Investigation: Sedighe Hosseini; Writing – original draft, resources: Elnaz Mousavi; Formal analysis: Imaneh Abasi; Review & editing: Abolfazl Mohammadi.
Conflict of interest
The authors declared no conflicts of interest.
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Article type: Original Research Articles |
Subject:
Psychology
Received: 2019/01/11 | Accepted: 2019/07/3 | Published: 2020/06/1
Received: 2019/01/11 | Accepted: 2019/07/3 | Published: 2020/06/1
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