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Showing 3 results for Ayazi
Cognitive Behavioral Group Therapy and Coping Styles in Patients with Acute Coronary Heart Disease
Freshte Oladi, Mohammad Hossein Bayazi , Mahmood Dargahi , Mohsen Dehghani Neishabouri ,
Volume 12, Issue 3 (September 2014)
Abstract

Objectives: The present study has investigated the effect of cognitive behavioral group therapy on improving coping styles in patients with acute coronary heart disease.

Methods: Semi-experimental in type of pretest-posttest with control group seems to be a good design for this study.22 patients with acute coronary heart disease are admitted in CCU of Mashhad Razavi Hospital and undergo angioplasty heart surgery,11 in the control and the other 11in the experimental group. Those in the experimental group receive 12 sessions of cognitive-behavioral group therapy and the ones in the control one are not offered any intervention. Before and after the intervention, CISS-21coping questionnaire is completed by members of the sample.

Results: The results of MANCOVA revealed after participating in cognitive behavioral group therapy, problem-oriented coping style of members of the experimental group than in the control group had a significant increase and avoidant coping style of members of the experimental group than in the control group had a significant reduction.

Discussion: Findings confirm that cognitive-behavioral group therapy improve coping styles in patients with acute coronary heart disease. Findings indicate awareness of thinking styles, identifying cognitive errors, doing cognitive homework, reinforcing positive behavior, encouraging acceptance of restrictions, sharing experiences, talking about negative emotions related to illness and the possible consequences.


Determination of Changes in Blood Biomarker Levels in Antipsychotic Polypharmacy and Aripiprazole Monotherapy in Patients With Long-term Schizophrenia
Venus Vatankhah, Arash Mirabzadeh, Hamidreza Iranpour, Bahman Dieji, Mehdi Norouzi, Morteza Karimipour, Jaleh Nobakht, Elham Esmaeili, Maryam Ayazi,
Volume 17, Issue 4 (December 2019)
Abstract
Objectives: Schizophrenia is a chronic psychiatric disorder, which reduces the patient’s quality of life. Although a minimum dose of medications has been recommended for treating this disorder, antipsychotic polypharmacy has been used experimentally leading to an increase in drug interactions. Aripiprazole is associated with a lower risk of metabolic side effects and is recommended as a first-line treatment for schizophrenia. Biomarkers can serve as predictive of treatment response in patients with schizophrenia. The aim of this study was to compare the efficacy of antipsychotic medication polypharmacy with Aripiprazole monotherapy in patients with long-term schizophrenia, using blood biomarkers.
Methods: Nineteen patients with long-term schizophrenia, who had received at least 2 types of antipsychotics with daily doses of more than 500 mg of chlorpromazine, were included in the study. The response rates to the treatment based on the Brief Psychiatric Rating Scale (BPRS) score and the blood level of Interleukin 2 (IL-2), Interleukin 6 (IL-6), Interleukin-1 Receptor Antagonist (IL-1RA), and Brain-derived Neurotrophic Factor (BDNF) biomarkers were compared in antipsychotic polypharmacy and 6 months after monotherapy with Aripiprazole.
Results: The mean concentrations of IL-6, IL-1RA, and IL-2 significantly decreased after the intervention. The mean changes in the BPRS scores and also the relationship between changes in blood biomarkers and BPRS scores after intervention were not significant.
Discussion: The conversion of the antipsychotic polypharmacy state to monotherapy with Aripiprazole has been accompanied by a significant decrease in the serum levels of IL-2, IL-6, and IL-1RA. These biomarkers can be used for evaluating the response rate of schizophrenia treatments in the future.

Language Sample Analysis in Children With Cleft Lip and Palate
Leila Safarpour, Nahid Jalilevand, Ali Ghorbani, Mahboobeh Rasouli, Gholamreza Bayazian,
Volume 19, Issue 1 (March 2021)
Abstract
Objectives: Cleft Palate (CP) with or without Cleft Lip (CL/P) are the most common craniofacial birth defects. Cleft Lip and Palate (CLP) can affect children’s communication skills. The present study aimed to evaluate language production skills concerning morphology and syntax (morphosyntactic) in children with CLP.
Methods: In the current cross-sectional study, 58 Persian-speaking children (28 children with CLP & 30 children without craniofacial anomalies=non-clefts) participated. Gathering the language samples of the children was conducted using the picture description method. The 50 consecutive intelligible utterances of children were analyzed by the Persian Developmental Sentence Scoring (PDSS), as a clinical morphosyntactic measurement tool.
Results: The PDSS total scores of children with CLP were lower than those of the non-clefts children. A significant difference was found between the studied children with CLP and children without craniofacial anomalies in the mean value of PDSS total scores (P=0.0001). 
Discussion: Children with CLP demonstrate a poor ability for using morphosyntactic elements. Therefore, it should be considered how children with CLP use the grammatical components.
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