988368
سه شنبه 18 آذر 1404
چکیده: (8 مشاهده)
Background. Chronic low back pain with radiculopathy is a disabling condition where conventional treatments often provide limited relief. Transcutaneous electrical nerve stimulation (TENS) and mesotherapy are promising modalities, yet their comparative efficacy is not well established. This study aimed to compare the effects of mesotherapy versus TENS on pain and functional disability in patients with MRI-confirmed lumbar radiculopathy.
Methods. This open-label randomized clinical trial included 60 patients with chronic radicular low back pain. Patients were allocated to either a TENS group (10 sessions of 100Hz stimulation) or a mesotherapy group (6 sessions of subcutaneous piroxicam and lidocaine injections). Pain intensity was measured using the Visual Analog Scale (VAS) and functional disability with the Roland-Morris Disability Questionnaire (RMQ) at baseline, immediately post-treatment, and at one- and two-month follow-ups.
Results. Both TENS (p < 0.001) and mesotherapy (p < 0.001) groups showed significant improvements in VAS and RMQ scores compared to their respective baselines. Immediately following the interventions, patients in the mesotherapy group demonstrated a significantly greater reduction in both pain (VAS) and RMQ scores than those in the TENS group. This superiority was maintained at the one- and two-month follow-up assessments, where the mesotherapy group continued to show significantly better outcomes. The therapeutic effect of TENS was transient, with scores at one and two months not being significantly different from baseline.
Conclusion. Mesotherapy provides a more potent and durable reduction in pain and disability compared to TENS for patients with chronic radicular low back pain. The sustained benefit of mesotherapy suggests it is a more robust therapeutic option for this condition, potentially creating a meaningful therapeutic window that allows patients to more effectively engage in active rehabilitation programs.
Methods. This open-label randomized clinical trial included 60 patients with chronic radicular low back pain. Patients were allocated to either a TENS group (10 sessions of 100Hz stimulation) or a mesotherapy group (6 sessions of subcutaneous piroxicam and lidocaine injections). Pain intensity was measured using the Visual Analog Scale (VAS) and functional disability with the Roland-Morris Disability Questionnaire (RMQ) at baseline, immediately post-treatment, and at one- and two-month follow-ups.
Results. Both TENS (p < 0.001) and mesotherapy (p < 0.001) groups showed significant improvements in VAS and RMQ scores compared to their respective baselines. Immediately following the interventions, patients in the mesotherapy group demonstrated a significantly greater reduction in both pain (VAS) and RMQ scores than those in the TENS group. This superiority was maintained at the one- and two-month follow-up assessments, where the mesotherapy group continued to show significantly better outcomes. The therapeutic effect of TENS was transient, with scores at one and two months not being significantly different from baseline.
Conclusion. Mesotherapy provides a more potent and durable reduction in pain and disability compared to TENS for patients with chronic radicular low back pain. The sustained benefit of mesotherapy suggests it is a more robust therapeutic option for this condition, potentially creating a meaningful therapeutic window that allows patients to more effectively engage in active rehabilitation programs.
