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Objectives: The aim of this study was to determine the effect of Perceptual-motor training on motor skills of normal preschool children (aged 4-6 years) in Esfahan city.

Methods: This was a quasi-experimental study with intervention and control groups. Each group included 30 normal preschool children aged 4 to 6 years. They were selected randomly children of intervention group one empowering children center and the control group from preschool centers, of Esfahan city in 2013. The intervention group received perceptual- motor training for 15 sessions (each 1 hour) during 2 months. The measurement was Bruninks–Oseretsky test that was implemented as pre and post-tests. Data analysis was done by SPSS version 18.

Results: The intervention group had significantly higher motor skills (gross and fine motor skills) scores after training, in comparison to control group (P=0.000).

Discussion: It seems that the perceptual-motor training can improve the motor skills level of preschool children. So it is recommended as a useful method for motivation of motor skills development in preschool centers.