Volume 16, Issue 1 (March 2018)                   IRJ 2018, 16(1): 17-24 | Back to browse issues page

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Samadi R, Razaghi Kashani E M, Kami M, Rezaei O. Executive Function and Attention Deficits in Post-Traumatic Stress Disorder: A Study on Iranian War Veterans. IRJ. 2018; 16 (1) :17-24
URL: http://irj.uswr.ac.ir/article-1-708-en.html
1- Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
3- MD Psychosis Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Abstract:   (191 Views)

Objectives: Patients with Post-Traumatic Stress Disorder (PTSD) show poor cognitive performance during neuropsychological tests. Literature is scarce regarding veterans suffering with chronic PTSD. Therefore, in this study, we aimed to compare the cognitive deficiencies of veterans with chronic PTSD with those of healthy participants.
Methods: A total of 51 hospitalized veterans and 45 healthy individuals were selected using a purposeful sampling method. Both groups performed a simple Stroop Test and the Continuous Performance Test (CPT) and completed the PTSD Checklist for DSM-5 (PCL-5).
Results: The results of independent samples t-test showed a significant difference in cognitive impairment between the veterans with PTSD and healthy subjects, and the veterans had lower performances on most aspects of the tests than that of the control group.
Discussion: According to our results, veterans with chronic PTSD showed lower cognitive performance than that of healthy individuals. This suggests that examination of the cognitive functioning of patients with PTSD can be useful in the diagnosis, prognosis, and treatment of PTSD.

Full-Text [PDF 529 kb]   (89 Downloads)    
Type of Study: Original Research Articles | Subject: Psychology
Received: 2017/10/5 | Accepted: 2018/01/1 | Published: 2018/03/1

1. Murthy RS, Lakshminarayana R. Mental health consequences of war: A brief review of research findings. World Psychiatry. 2006; 5(1):25-30. PMCID: PMC1472271 [PMID] [PMCID]
2. American Psychology Association. Diagnostic and statistical manual of mental disorders (DSM-5®). New York: American Psychology Association Pub; 2013.
3. Sadock BJ, Sadock VA. Kaplan and Sadock's synopsis of psychiatry: Behavioral sciences/clinical psychiatry. Philadelphia: Lippincott Williams & Wilkins; 2011.
4. Mohammadi M-R, Davidian H, Noorbala AA, Malekafzali H, Naghavi HR, Pouretemad HR, et al. An epidemiological survey of psychiatric disorders in Iran. Clinical Practice and Epidemiology in Mental Health. 2005; 1:16. Available from: http://dx.doi.org/10.1186/1745-0179-1-16 [DOI:10.1186/1745-0179-1-16]
5. Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB. Posttraumatic stress disorder in the National Comorbidity Survey. Archives of General Psychiatry. 1995; 52(12):1048-60. Available from: http://dx.doi.org/10.1001/archpsyc.1995.03950240066012 [DOI:10.1001/archpsyc.1995.03950240066012]
6. Vasterling JJ, Brewin C. Neuropsychology of PTSD: Biological, cognitive, and clinical perspectives. New York: Guilford Press; 2005.
7. Aupperle RL, Melrose AJ, Stein MB, Paulus MP. Executive function and PTSD: Disengaging from trauma. Neuropharmacology. 2012; 62(2):686-94. Available from: http://dx.doi.org/10.1016/j.neuropharm.2011.02.008 [DOI:10.1016/j.neuropharm.2011.02.008]
8. Flaks MK, Malta SM, Almeida PP, Bueno OF, Pupo MC, Andreoli SB, et al. Attentional and executive functions are differentially affected by post-traumatic stress disorder and trauma. Journal of Psychiatric Research. 2014; 48(1):32-9. Available from: http://dx.doi.org/10.1016/j.jpsychires.2013.10.009 [DOI:10.1016/j.jpsychires.2013.10.009]
9. Ghasemi N, Kiani A, Zerehposh A, Rabiei M, Vakili N. [The Study of the Differences of Attention Bias, Executive Functioning, and Reaction Time of Amphetamine Consumers in Comparison of Non Consumers (Persian)]. E'tiad Pazhoohi. 2012; 23(6):53-64.
10. Denckla, M. B. (1996). A theory and model of executive function: A neuropsychological perspective. In Lyon GR, & Krasnegor NA editors. Attention, Memory, and Executive Function. Baltimore: Paul H Brookes Publishing.
11. Kanagaratnam P, Asbjørnsen AE. Executive deficits in chronic PTSD related to political violence. Journal of anxiety disorders. 2007; 21(4):510-25. Available from: http://dx.doi.org/10.1016/j.janxdis.2006.06.008 [DOI:10.1016/j.janxdis.2006.06.008]
12. Koso M, Hansen S. Executive function and memory in posttraumatic stress disorder: a study of Bosnian war veterans. European Psychiatry. 2006; 21(3):167-73. Available from: http://dx.doi.org/10.1016/j.eurpsy.2005.06.004 [DOI:10.1016/j.eurpsy.2005.06.004]
13. Meewisse ML, Nijdam MJ, de Vries GJ, Gersons BP, Kleber RJ, van der Velden PG, et al. Disaster-related posttraumatic stress symptoms and sustained attention: Evaluation of depressive symptomatology and sleep disturbances as mediators. Journal of Traumatic Stress. 2005; 18(4):299-302. Available from: http://dx.doi.org/10.1002/jts.20037 [DOI:10.1002/jts.20037]
14. Mehdizadeh M, Rezaei O. Third-person diagnostic interview on the cognitive insight level of psychotic patients with an insight at the denial level. Indian journal of psychological medicine. 2016; 38(3):217. Available from: http://dx.doi.org/10.4103/0253-7176.183088 [DOI:10.4103/0253-7176.183088]
15. Brewin C, Beaton A. Thought suppression, intelligence, and working memory capacity. Behaviour Research and Therapy. 2002; 40(8):923-30. Available from: http://dx.doi.org/10.1016/s0005-7967(01)00127-9 [DOI:10.1016/S0005-7967(01)00127-9]
16. Shiffrin RM, Schneider W. Automatic and controlled processing revisited. 1984; 91(2):269-76. PMID: 6571425
17. McFarlane AC, Weber DL, Clark CR. Abnormal stimulus processing in posttraumatic stress disorder. Biological Psychiatry. 1993; 34(5):311-20. Available from: http://dx.doi.org/10.1016/0006-3223(93)90088-u [DOI:10.1016/0006-3223(93)90088-U]
18. Dunkin JJ, Leuchter AF, Cook IA, Kasl-Godley JE, Abrams M, Rosenberg-Thompson S. Executive dysfunction predicts nonresponse to fluoxetine in major depression. Journal of Affective Disorders. 2000; 60(1):13–23. Available from: http://dx.doi.org/10.1016/s0165-0327(99)00157-3 [DOI:10.1016/S0165-0327(99)00157-3]
19. Improving Attention and Managing Attentional Problems. Annals of the New York Academy of Sciences. Wiley-Blackwell; 2006; 931(1):359–75. Available from: http://dx.doi.org/10.1111/j.1749-6632.2001.tb05790.x [DOI:10.1111/j.1749-6632.2001.tb05790.x]
20. Golden CJ. The Measurement of Creativity by the Stroop Color and Word Test. Journal of Personality Assessment. 1975; 39(5):502–6. Available from: http://dx.doi.org/10.1207/s15327752jpa3905_9 [DOI:10.1207/s15327752jpa3905_9]
21. Gokalsing E, Robert P., Lafont V, Medecin I, Baudu C, Boyer P, et al. Evaluation of the supervisory system in elderly subjects with and without disinhibition. European Psychiatry. 2000; 15(7):407–15. Available from: http://dx.doi.org/10.1016/s0924-9338(00)00511-3 [DOI:10.1016/S0924-9338(00)00511-3]
22. Cornblatt B, Obuchowski M, Roberts S, Pollack S, Erlenmeyer–Kimling L. Cognitive and behavioral precursors of schizophrenia. Development and Psychopathology. 1999; 11(3):487–508. Available from: http://dx.doi.org/10.1017/s0954579499002175 [DOI:10.1017/S0954579499002175]
23. Bovin MJ, Marx BP, Weathers FW, Gallagher MW, Rodriguez P, Schnurr PP, et al. Psychometric properties of the PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders–Fifth Edition (PCL-5) in veterans. Psychological Assessment. 2016; 28(11):1379–91. Available from: http://dx.doi.org/10.1037/pas0000254 [DOI:10.1037/pas0000254]
24. Blevins CA, Weathers FW, Davis MT, Witte TK, Domino JL. The Posttraumatic Stress Disorder Checklist forDSM-5(PCL-5): Development and Initial Psychometric Evaluation. Journal of Traumatic Stress. 2015; 28(6):489–98. Available from: http://dx.doi.org/10.1002/jts.22059 [DOI:10.1002/jts.22059]
25. Mirdoraghi F, Ghanbari Hashemabadi B, Mashhadi A. [Deficiencies of Executive Functions in patients with Posttraumatic Stress Disorder (Persian)]. Iranian Journal of War and Public Health. 2012; 5(1):27-35.
26. Mirdoraghi F, Hashemabady G, Mashhadi A. [Cognitive and behavioral inhibition in veterans with-and without post traumatic stress disorder (Persian)]. Journal of Military Medicine. 2012; 14(1):41-7.
27. Olff M, Polak AR, Witteveen AB, Denys D. Executive function in posttraumatic stress disorder (PTSD) and the influence of comorbid depression. Neurobiology of Learning and Memory. 2014; 112:114–21. Available from: http://dx.doi.org/10.1016/j.nlm.2014.01.003 [DOI:10.1016/j.nlm.2014.01.003]
28. Mehdizadeh M, Rezaei O, Dolatshahi B. Determining the effectiveness of the third person interview in the level of insight psychotic patients. Psychiatry research. 2016; 245:238-42. Available from: http://dx.doi.org/10.1016/j.psychres.2016.08.001 [DOI:10.1016/j.psychres.2016.08.001]
29. Jurado MB, Rosselli M. The Elusive Nature of Executive Functions: A Review of our Current Understanding. Neuropsychology Review. 2007; 17(3):213–33. Available from: http://dx.doi.org/10.1007/s11065-007-9040-z [DOI:10.1007/s11065-007-9040-z]
30. Lezak MD. Neuropsychological assessment. Oxford: Oxford University Press; 2004.
31. Shin LM, Rauch SL, Pitman RK. Amygdala, Medial Prefrontal Cortex, and Hippocampal Function in PTSD. Annals of the New York Academy of Sciences. 2006; 1071(1):67–79. Available from: http://dx.doi.org/10.1196/annals.1364.007 [DOI:10.1196/annals.1364.007]
32. Matsuo K, Taneichi K, Matsumoto A, Ohtani T, Yamasue H, Sakano Y, et al. Hypoactivation of the prefrontal cortex during verbal fluency test in PTSD: A near-infrared spectroscopy study. Psychiatry Research: Neuroimaging. 2003; 124(1):1–10. Available from: http://dx.doi.org/10.1016/s0925-4927(03)00093-3 [DOI:10.1016/S0925-4927(03)00093-3]
33. Polak AR, Witteveen AB, Reitsma JB, Olff M. The role of executive function in posttraumatic stress disorder: A systematic review. Journal of Affective Disorders. 2012; 141(1):11–21. Available from: http://dx.doi.org/10.1016/j.jad.2012.01.001 [DOI:10.1016/j.jad.2012.01.001]
34. Twamley EW, Allard CB, Thorp SR, Norman SB, Cissell SH, Berardi KH, et al. Cognitive impairment and functioning in PTSD related to intimate partner violence. Journal of the International Neuropsychological Society. 2009; 15(06):879. Available from: http://dx.doi.org/10.1017/s135561770999049x [DOI:10.1017/S135561770999049X]
35. Breton F, Planté A, Legauffre C, Morel N, Adès J, Gorwood P, et al. The executive control of attention differentiates patients with schizophrenia, their first-degree relatives and healthy controls. Neuropsychologia. 2011; 49(2):203–8. Available from: http://dx.doi.org/10.1016/j.neuropsychologia.2010.11.019 [DOI:10.1016/j.neuropsychologia.2010.11.019]
36. Swanson JM. Role of executive function in ADHD. Journal of Clinical Psychiatry. 2003; 64(S14):35-9. PMID: 14658934 [PMID]
37. Koenigs M, Grafman J. Posttraumatic Stress Disorder: The Role of Medial Prefrontal Cortex and Amygdala. Neuroscientist. 2009; 15(5):540–8. Available from: http://dx.doi.org/10.1177/1073858409333072 [DOI:10.1177/1073858409333072]
38. Tan L, Zhang L, Qi R, Lu G, Li L, Liu J, et al. Brain structure in post-traumatic stress disorder: A voxel-based morphometry analysis. Neural Regeneration Research. 2013; 8(26):2405. Available from: http://dx.doi.org/10.3969/j.issn.1673-5374.2013.26.001

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